The novel combination of naturally sourced caffeine and stress-modulating adaptogens found in e+™ energy shot is what sets it apart from any other energy drink on the market. It’s this unique blend of ingredients that also make its function extremely versatile.

Based on its design and formulation, the scientific literature on caffeine and adaptogens suggest a few different ways that you can incorporate the energy drink. Whether before a workout or as a caffeinated pick-me-up, e+ can provide you long-lasting energy.

1.First Thing in the Morning

About one in four people in the United States seek out coffee or some other form of caffeinated beverage every morning. For extra stress-modulating support, Isagenix product users might also take Ionix® Supreme for its content of botanicals called adaptogens that can help increase mental alertness and focus (1, 2).

Why not start off the day with the combination of caffeine plus adaptogens? We’re not suggesting giving up coffee or Ionix, as these products can offer their own benefits. But on those busier days, e+ can provide about as much caffeine as that of a cup of coffee. In addition, e+ provides a moderate dose of adaptogens for those times when taking a quick shot is more convenient.

2. A Mid-Day Pick-Me-Up

Getting stuck in a midday slump can kill your productivity. A good second dose of caffeine at the middle of the day can be what you need to sharpen your mind and fight fatigue (3,4). A shot of e+ can help you power through your day.

3. Preworkout

It’s not news that e+ is often used in conjunction with AMPED Power and NOx as part of a pre-workout stack. The caffeine supplied by e+ is valued by athletes and gym-goers alike.

Caffeine’s effects on improving exercise performance, reducing perception of effort, and reducing fatigue have been demonstrated time and again in scientific studies involving athletes of all types (5-7).

In addition, the adaptogens found in e+ have been studied for their effects on improving both mental and athletic performance (8,9).

4. Midworkout

For the same reasons that so many athletes rely on caffeine preworkout, taking an e+ shot midworkout can help endurance athletes finish strong. One study found that athletes who ingested a carbohydrate gel (such as AMPED™ Fuel) alongside a moderate dose of caffeine during a long workout enhanced their use of glucose during competition due to increased intestinal absorbability (10). The combination helped to fuel the athletes and reduce their reliance on muscle glycogen midworkout.

5. Cleanse Day Support

When Cleanse Days become difficult, one of the easiest support tools is an e+ shot. Some people may experience either natural caffeine withdrawal symptoms or low blood sugar during intermittent fasting. The combination of a moderate dose of caffeine and a few grams of sugar from juice concentrates can supply a steady rise of energy that is just what’s needed on a Cleanse Day. Contributing just 30 calories, a shot fits easily into your Cleanse Day schedule.

As an important reminder, recommendations are to limit e+ shots to only two per day. This precaution is intended to avoid overuse of the supplement. However, the many ways you can use e+ should help ensure that you’re taking advantage of its versatility on a regular basis as part of your daily lifestyle.


  1. Panossian A, Wikman G. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol. 2009 Sep;4(3):198-219. Epub 2009 Sep 1.
  2. Panossian A, Wikman G. Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity. Pharmaceuticals (Basel). 2010 Jan; 3(1): 188–224. Published online 2010 Jan 19. doi: 3390/ph3010188
  3. Wyatt JK, Cajochen C, Ritz-De Cecco A, Czeisler CA, Dijk DJ. Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness. Sleep. 2004 May 1;27(3):374-81.
  4. Wilhelmus MM, Hay JL, Zuiker RG, Okkerse P, Perdrieu C, Sauser J, Beaumont M, Schmitt J, van Gerven JM, Silber BY. Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects. J Psychopharmacol. 2017 Feb;31(2):222-232. doi: 10.1177/0269881116668593. Epub 2016 Sep 27.
  5. Desbrow B, Biddulph C, Devlin B, Grant GD, Anoopkumar-Dukie S, and Leveritt MD. The effects of different doses of caffeine on endurance cycling time trial performance. J Sports Sci. 2012; 30(2): 115-20. doi: 1080/02640414.2011.632431.
  6. Hodgson AB, Randell RK, and Jeukendrup AE. The metabolic and performance effects of caffeine compared to coffee during endurance exercise. PLoS One. 2013 Apr; 8(4): e59561. doi: 1371/journal.pone.0059561.
  7. O’Rourke MP, O’Brien BJ, Knez WL, and Paton CD. Caffeine has a small effect on 5-km running performance of well-trained and recreational runners. J Sci Med Sport. 2008 Apr 30;11(2):231-3.
  8. Kuo J, Chen KW, Cheng IS, Tsai PH, Lu YJ, Lee NY. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human. Chin J Physiol. 2010 Apr 30;53(2):105-11.
  9. Amagase H, Sun B, Borek C. Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults. Nutr Res. 2009 Jan;29(1):19-25. doi: 10.1016/j.nutres.2008.11.005.
  10. Yeo SE, Jentjens RL, Wallis GA, Jeukendrup AE. Caffeine increases exogenous carbohydrate oxidation during exercise. J Appl Physiol (1985). 2005 Sep;99(3):844-50. Epub 2005 Apr 14.